In this quote, Marcus Aurelius encourages us to embrace our nature and do our job as human beings. He reminds us that we were born to do things and experience them, not just to feel 'nice' and stay comfortable. He also points out that people who love what they do wear themselves down doing it, and that we should have more respect for our own nature and what it demands of us. This quote serves as a great motivation for anyone who needs a reminder to embrace their true nature and do what they were born to do.